TY - GEN AU - Varga, John J AU - Barbier, Mariette AU - Mulet, Xavier AU - Bielecki, Piotr AU - Bartell, Jennifer A AU - Owings, Joshua P AU - Martinez-Ramos, Inmaculada AU - Hittle, Lauren E AU - Davis, Michael R., Jr AU - Damron, F. Heath AU - Liechti, George W AU - Puchalka, Jacek AU - dos Santos, Vitor Martins AU - Ernst, Robert K AU - Papin, Jason A AU - Alberti, Sebastian AU - Oliver, Antonio AU - Goldberg, Joanna B. PY - 2015 DO - 10.1186/s12864-015-2069-0 SN - 1471-2164 UR - http://hdl.handle.net/20.500.12105/20156 AB - Background: Pseudomonas aeruginosa is an environmentally ubiquitous Gram-negative bacterium and important opportunistic human pathogen, causing severe chronic respiratory infections in patients with underlying conditions such as cystic fibrosis (CF)... LA - eng PB - BioMed Central (BMC) KW - Pseudomonas aeruginosa KW - Metabolic model KW - Transcriptome KW - Comparative genomics KW - Cystic fibrosis KW - Bronchiectasis KW - Genotype KW - Anti-Bacterial Agents KW - Secondary Metabolism KW - Microbial Sensitivity Tests KW - Molecular Sequence Data KW - Alleles KW - Humans KW - Cystic Fibrosis KW - Adaptation, Biological KW - Phenotype KW - High-Throughput Nucleotide Sequencing KW - Quorum Sensing KW - Pseudomonas aeruginosa KW - Chronic Disease KW - Pseudomonas Infections KW - Bacterial Proteins KW - Bronchiectasis KW - Genome, Bacterial KW - Biofilms KW - Computational Biology KW - Drug Resistance, Bacterial KW - Transcriptome KW - Mutation Rate KW - Mutation KW - Gene Expression Profiling KW - Gene Order KW - Genomics KW - Virulence TI - Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains TY - research article ER -