TY  - GEN
AU  - Lopez-Arguello, Silvia
AU  - Montaner, Maria
AU  - Oliver, Antonio
AU  - Moya, Bartolome
PY  - 2021
DO  - 10.3390/ijms22063051
UR  - https://hdl.handle.net/20.500.12105/23282
AB  - Avibactam belongs to the new class of diazabicyclooctane beta-lactamase inhibitors. Its inhibitory spectrum includes class A, C and D enzymes, including P. aeruginosa AmpC. Nonetheless, recent reports have revealed strain-dependent avibactam AmpC...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - Penicillin-binding proteins
KW  - PBP
KW  - Avibactam
KW  - AmpC induction
KW  - PDC
KW  - β-lactam resistance
KW  - ST175
KW  - Bacterial Proteins
KW  - Microbial Sensitivity Tests
KW  - Humans
KW  - Penicillin-Binding Proteins
KW  - Drug Resistance, Bacterial
KW  - Inhibitory Concentration 50
KW  - Cefoxitin
KW  - Mutation
KW  - Azabicyclo Compounds
KW  - beta-Lactamases
KW  - Gene Expression Regulation, Bacterial
KW  - Pseudomonas aeruginosa
KW  - Imipenem
TI  - Molecular Basis of AmpC beta-Lactamase Induction by Avibactam in Pseudomonas aeruginosa: PBP Occupancy, Live Cell Binding Dynamics and Impact on Resistant Clinical Isolates Harboring PDC-X Variants
TY  - research article
ER  -