TY  - JOUR
AU  - Mayor-Ruiz, Cristina
AU  - Olbrich, Teresa
AU  - Drosten, Matthias
AU  - Lecona, Emilio
AU  - Vega-Sendino, Maria
AU  - Ortega Jimenez, Sagrario
AU  - Dominguez, Orlando
AU  - Barbacid, Mariano
AU  - Ruiz, Sergio
AU  - Fernandez-Capetillo, Oscar
PY  - 2018
DO  - 10.1101/gad.310086.117
SN  - 0890-9369
UR  - http://hdl.handle.net/20.500.12105/8360
AB  - MEK inhibition in combination with a glycogen synthase kinase-3β (GSK3β) inhibitor, referred as the 2i condition, favors pluripotency in embryonic stem cells (ESCs). However, the mechanisms by which the 2i condition limits ESC differentiation and...
LA  - eng
PB  - Cold Spring Harbor Laboratory Press
KW  - 2i
KW  - ERF
KW  - RAS
KW  - mESCs
KW  - Pluripotency
KW  - Animals
KW  - Cell Differentiation
KW  - Cell Line
KW  - Embryonic Stem Cells
KW  - Enhancer Elements, Genetic
KW  - Gene Deletion
KW  - Mice
KW  - Mice, Nude
KW  - Repressor Proteins
KW  - Teratoma
KW  - Genes, ras
TI  - ERF deletion rescues RAS deficiency in mouse embryonic stem cells
TY  - journal article
ER  -