TY - GEN AU - Escudero-Contreras, Alejandro AU - López-Medina, Clementina AU - Collantes-Estévez, Eduardo AU - Ortega-Castro, Rafaela AU - Calvo-Gutiérrez, Jerusalem AU - Mena-Vázquez, Natalia AU - Panero-Lamothe, Blanca AU - Manzanares-Martín, Bárbara AU - Cáliz-Cáliz, Rafael AU - Jiménez-Morales, Alberto AU - Ruiz-Jiménez, Mayte AU - Font-Ugalde, Pilar PY - 2021 DO - 10.3390/jcm10184070 UR - http://hdl.handle.net/20.500.12105/18461 AB - Objective: to identify new single-nucleotide polymorphisms (SNPs) in genes encoding proteins involved in methotrexate (MTX) metabolism and to evaluate the associations of these SNPs with MTX toxicity or intolerance in a southern Spanish cohort of... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Methotrexate KW - Rheumatoid arthritis KW - Genetics KW - Biomarkers KW - Metotrexato KW - Artritis reumatoide KW - Genética KW - Biomarcadores KW - Polimorfismo genético KW - Genetic polymorphisms KW - Genotype KW - Genotipo KW - Humans KW - Methotrexate KW - Polymorphism, Single Nucleotide KW - Retrospective Studies KW - Spain KW - Arthritis, Rheumatoid KW - Genotype KW - Nucleotides KW - Multicenter Studies as Topic TI - Genetic Polymorphisms of GGH and ABCC2 Are Associated with Methotrexate Intolerance in Patients with Rheumatoid Arthritis TY - research article ER -