TY - JOUR AU - Rodriguez Antona, Cristina AU - Leskelä, Susanna AU - Zajac, Magdalena AU - Cuadros, Marta AU - Alvés, Javier AU - Moneo, Maria Victoria AU - Martín, Carmen AU - Cigudosa, Juan Cruz AU - Carnero, Amancio AU - Robledo Batanero, Mercedes AU - Benitez, Javier AU - Martínez-Delgado, Beatriz PY - 2007 DO - 10.1182/blood-2007-02-075036 SN - 0006-4971 UR - http://hdl.handle.net/20.500.12105/17493 AB - Peripheral T-cell lymphomas (PTCLs) are aggressive tumors in which the current therapy based on multiagent chemotherapy is not successful. Since cytochrome P450 3A subfamily (CYP3A) enzymes are involved in the inactivation of chemotherapy drugs, we... LA - eng PB - Elsevier KW - ATP Binding Cassette Transporter, Subfamily B KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - Antineoplastic Agents KW - Chromosomes, Human, Pair 7 KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme System KW - Doxorubicin KW - Drug Resistance, Neoplasm KW - Etoposide KW - Gene Duplication KW - Gene Expression KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Jurkat Cells KW - Lymphoma, T-Cell, Peripheral KW - Prognosis KW - Survival Analysis KW - Treatment Outcome KW - Tumor Cells, Cultured TI - Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas. TY - journal article ER -