TY - GEN AU - Bueno, Clara AU - Torres-Ruiz, Raul AU - Velasco-Hernandez, Talia AU - Molina, Oscar AU - Petazzi, Paolo AU - Martinez, Alba AU - Rodriguez, Virginia AU - Vinyoles, Meritxell AU - Cantilena, Sandra AU - Williams, Owen AU - Vega-Garcia, Nerea AU - Rodriguez Perales, Sandra AU - Segovia, Jose C AU - Quintana-Bustamante, Oscar AU - Roy, Anindita AU - Meyer, Claus AU - Marschalek, Rolf AU - Smith, Alastair L AU - Milne, Thomas A AU - Fraga, Mario F AU - Tejedor, Juan Ramón AU - Menéndez, Pablo PY - 2023 UR - https://hdl.handle.net/20.500.12105/26144 AB - Cellular ontogeny and MLL breakpoint site influence the capacity of MLL-edited CD34+ hematopoietic cells to initiate and recapitulate infant patients' features in pro-B-cell acute lymphoblastic leukemia (B-ALL). We provide key insights into the... LA - eng PB - Elsevier KW - ACUTE LEUKEMIAS KW - RECOMBINOME KW - BREAKPOINTS KW - BIOLOGY KW - MLL-AF4 TI - A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features. TY - letter to the editor ER -