TY  - JOUR
AU  - Torres-Ruiz Raul, Raul
AU  - Martinez-Lage, Marta
AU  - Martin, Maria C
AU  - Garcia, Aida
AU  - Bueno, Clara
AU  - Castaño, Julio
AU  - Ramirez, Juan C
AU  - Menéndez, Pablo
AU  - Cigudosa, Juan C
AU  - Rodriguez Perales, Sandra
PY  - 2017
DO  - 10.1016/j.stemcr.2017.04.014
SN  - 22136711
UR  - http://hdl.handle.net/20.500.12105/7238
AB  - Efficient methodologies for recreating cancer-associated chromosome translocations are in high demand as tools for investigating how such events initiate cancer. The CRISPR/Cas9 system has been used to reconstruct the genetics of these complex...
LA  - eng
PB  - Elsevier
KW  - CRISPR
KW  - Cas9
KW  - Ewing sarcoma
KW  - MSC
KW  - Cancer modeling
KW  - Cancer translocation
KW  - Disease model
KW  - Genome engineering
KW  - Human stem cells
KW  - iPSC
KW  - Gene Targeting
KW  - HEK293 Cells
KW  - Humans
KW  - Induced Pluripotent Stem Cells
KW  - Mesenchymal Stem Cells
KW  - Oncogene Proteins, Fusion
KW  - Sarcoma, Ewing
KW  - CRISPR-Cas Systems
KW  - Translocation, Genetic
TI  - Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9
TY  - journal article
ER  -