TY - JOUR AU - Simón-Carrasco, Lucía AU - Jiménez, Gerardo AU - Barbacid, Mariano AU - Drosten, Matthias PY - 2018 DO - 10.1080/15384101.2018.1450029 UR - http://hdl.handle.net/20.500.12105/14774 AB - The transcriptional repressor Capicua (CIC) has emerged as an important rheostat of cell growth regulated by RAS/MAPK signaling. Cic was originally discovered in Drosophila, where it was shown to be inactivated by MAPK signaling downstream of the RTKs... LA - eng PB - Taylor & Francis KW - Signal Transduction KW - Animals KW - Drosophila KW - Drug Resistance, Neoplasm KW - Gene Expression Regulation, Developmental KW - Humans KW - Neoplasms KW - Protein Isoforms KW - Repressor Proteins KW - ras Proteins TI - The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer. TY - journal article ER -