TY  - JOUR
AU  - Pattwell, Siobhan S
AU  - Arora, Sonali
AU  - Cimino, Patrick J
AU  - Ozawa, Tatsuya
AU  - Szulzewsky, Frank
AU  - Hoellerbauer, Pia
AU  - Bonifert, Tobias
AU  - Hoffstrom, Benjamin G
AU  - Boiani, Norman E
AU  - Bolouri, Hamid
AU  - Correnti, Colin E
AU  - Oldrini, Barbara
AU  - Silber, John R
AU  - Paddison, Patrick J
AU  - Holland, Eric C
AU  - Squatrito, Massimo
PY  - 2020
DO  - 10.1038/s41467-020-16786-5
UR  - http://hdl.handle.net/20.500.12105/12179
AB  - Independent scientific achievements have led to the discovery of aberrant splicing patterns in oncogenesis, while more recent advances have uncovered novel gene fusions involving neurotrophic tyrosine receptor kinases (NTRKs) in gliomas. The...
LA  - eng
PB  - Nature Publishing Group
KW  - RNA Splicing
KW  - Animals
KW  - Brain
KW  - Brain Neoplasms
KW  - Carcinogenesis
KW  - Cells, Cultured
KW  - Gene Expression Profiling
KW  - Gene Ontology
KW  - Glioma
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Membrane Glycoproteins
KW  - Mice
KW  - NIH 3T3 Cells
KW  - Neural Stem Cells
KW  - Oncogene Proteins, Fusion
KW  - Oncogenes
KW  - Phosphatidylinositol 3-Kinases
KW  - RNA Isoforms
KW  - Receptor, trkB
KW  - Signal Transduction
TI  - A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
TY  - journal article
ER  -