TY - JOUR AU - Vilas, Jéssica M AU - Carneiro, Carmen AU - Da Silva-Álvarez, Sabela AU - Ferreirós, Alba AU - Gonzalez Garcia, Patricia AU - Gomez Gil, Maria AU - Ortega Jimenez, Sagrario AU - Serrano Marugan , Manuel AU - García-Caballero, Tomás AU - González-Barcia, Miguel AU - Vidal, Anxo AU - Collado, Manuel PY - 2018 DO - 10.1111/acel.12834 SN - 14749718 UR - http://hdl.handle.net/20.500.12105/6593 AB - Aging is characterized by a gradual functional decline of tissues with age. Adult stem and progenitor cells are responsible for tissue maintenance, repair, and regeneration, but during aging, this population of cells is decreased or its activity is... LA - eng PB - Wiley KW - Sox2 KW - Adult stem cells KW - Aging KW - Stem cell exhaustion TI - Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging TY - journal article ER -