TY - GEN AU - Blanco-Martín, Tania AU - Alonso-García, Isaac AU - González-Pinto, Lucía AU - Outeda-García, Michelle AU - Guijarro-Sánchez, Paula AU - López-Hernández, Inmaculada AU - Perez-Vazquez, Maria AU - Aracil, Belen AU - López-Cerero, Lorena AU - Fraile-Ribot, Pablo AU - Oliver, Antonio AU - Vázquez-Ucha, Juan Carlos AU - Beceiro, Alejandro AU - Bou, Germán AU - Arca-Suárez, Jorge AU - GEMARA/SEIMC-CIBERINFEC Study Group on the activity and resistance mechanisms to new β-lactams and β-lactamase inhibitors (PROTECT) PY - 2024 DO - 10.1016/j.ijantimicag.2024.107150 UR - http://hdl.handle.net/20.500.12105/19906 AB - Objectives: To analyse the impact of the most clinically relevant β-lactamases and their interplay with low outer membrane permeability on the activity of cefiderocol, ceftazidime/avibactam, aztreonam/avibactam, cefepime/enmetazobactam,... LA - eng PB - Elsevier KW - β-lactamases KW - Cefiderocol KW - β-lactam/β-lactamase inhibitor KW - Combinations KW - Permeability KW - Double-carbapenemase KW - Escherichia coli KW - Escherichia coli KW - beta-Lactamases KW - Cephalosporins KW - Microbial Sensitivity Tests KW - beta-Lactamase Inhibitors KW - Azabicyclo Compounds KW - Anti-Bacterial Agents KW - Drug Combinations KW - Cyclooctanes KW - Cefiderocol KW - Ceftazidime KW - Cefepime KW - Borinic Acids KW - Carboxylic Acids KW - Lactams KW - Triazoles KW - Boronic Acids KW - Meropenem KW - Aztreonam KW - Imipenem KW - Bacterial Proteins KW - Heterocyclic Compounds, 1-Ring KW - Cell Membrane Permeability TI - Activity of cefiderocol and innovative β-lactam/β-lactamase inhibitor combinations against isogenic strains of Escherichia coli expressing single and double β-lactamases under high and low permeability conditions TY - research article ER -