TY - GEN AU - Perez, Marco AU - Lucena-Cacace, Antonio AU - Marín-Gómez, Luis Miguel AU - Padillo-Ruiz, Javier AU - Robles-Frias, Maria Jose AU - Saez, Carmen AU - Garcia-Carbonero, Rocio AU - Carnero, Amancio PY - 2016 DO - 10.18632/oncotarget.8880 UR - https://hdl.handle.net/20.500.12105/25220 AB - Despite the development of new antineoplastic agents for the treatment of colorectal cancer (CRC), oxaliplatin and fluoropyrimidines remain the most commonly employed drugs for the treatment of both early and advanced disease. Intrinsic or acquired... LA - eng KW - Src kinase KW - Biomarkers KW - Cancer treatment KW - Metastatic colorectal carcinoma KW - pdx models KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - Dasatinib KW - Drug Synergism KW - Female KW - Humans KW - Liver Neoplasms KW - Mice KW - Mice, Nude KW - Neoplasm Metastasis KW - Organoplatinum Compounds KW - Oxaliplatin KW - Transfection KW - src-Family Kinases TI - Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src TY - research article ER -