TY - GEN AU - Piñeiro-Sabarís, Rebeca AU - MacGrogan, Donal AU - de la Pompa, José Luis AU - Piñeiro-Sabarís, Rebeca AU - MacGrogan, Donal AU - de la Pompa, José Luis PY - 2024 UR - https://hdl.handle.net/20.500.12105/25813 AB - The cardiac outflow tract (OFT) transiently links the ventricles to the aortic sac and forms the arterial valves. Abnormalities in these valves, such as bicuspid aortic valve (BAV), are common congenital anomalies. GATA6-inactivating variants cause... LA - eng PB - The Company of Biologists KW - ACKR3/CXCR7 KW - Bicuspid aortic valve KW - Cardiac neural crest KW - Endocardial cushion development KW - GATA6 KW - Outflow tract TI - Deficient GATA6-CXCR7 signaling leads to bicuspid aortic valve. TY - review article ER -