TY - GEN AU - Mateu-Borrás, Margalida AU - Zamorano, Laura AU - Gonzalez-Alsina, Alex AU - Sanchez-Diener, Irin AU - Doménech-Sánchez, Antonio AU - Oliver, Antonio AU - Alberti, Sebastian PY - 2022 DO - 10.3389/fcimb.2021.816356 SN - 2235-2988 UR - https://hdl.handle.net/20.500.12105/23482 AB - Pseudomonas aeruginosa is a major cause of nosocomial bloodstream infections. This microorganism secretes two major proteases, alkaline protease A (AprA) and elastase B (LasB). Despite several in vitro studies having demonstrated that both purified... LA - eng PB - Frontiers Media KW - Alkaline protease KW - Elastase B KW - Complement component C3 KW - Bloodstream infection KW - Pseudomonas aeruginosa KW - Bacterial Proteins KW - Sepsis KW - Animals KW - Pancreatic Elastase KW - Endopeptidases KW - Metalloendopeptidases KW - Pseudomonas aeruginosa KW - Virulence KW - Mice KW - Pseudomonas Infections TI - Molecular Analysis of the Contribution of Alkaline Protease A and Elastase B to the Virulence of Pseudomonas aeruginosa Bloodstream Infections TY - research article ER -