TY  - JOUR
AU  - Hernández-Jiménez, Macarena
AU  - Martín-Vílchez, Samuel
AU  - Ochoa, Dolores
AU  - Mejía-Abril, Gina
AU  - Román, Manuel
AU  - Camargo-Mamani, Paola
AU  - Luquero-Bueno, Sergio
AU  - Jilma, Bernd
AU  - Moro, María A
AU  - Fernández, Gerónimo
AU  - Piñeiro, David
AU  - Ribó, Marc
AU  - González, Victor M
AU  - Lizasoain, Ignacio
AU  - Abad-Santos, Francisco
PY  - 2022
DO  - 10.1016/j.omtn.2022.03.005
SN  - 2162-2531
UR  - http://hdl.handle.net/20.500.12105/15724
AB  - ApTOLL is an aptamer that antagonizes Toll-like receptor 4 and improves functional outcomes in models of ischemic stroke and myocardial infarction. The aim of this study was to characterize the safety and pharmacokinetics of ApTOLL in healthy...
LA  - eng
PB  - Cell Press
TI  - First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers.
TY  - journal article
ER  -