TY  - GEN
AU  - Avila-Pedretti, Gabriela
AU  - Tornero, Jesús
AU  - Fernández-Nebro, Antonio
AU  - Blanco, Francisco
AU  - González-Alvaro, Isidoro
AU  - Cañete, Juan D
AU  - Maymó, Joan
AU  - Alperiz, Mercedes
AU  - Fernández-Gutiérrez, Benjamín
AU  - Olivé, Alex
AU  - Corominas, Héctor
AU  - Erra, Alba
AU  - Aterido, Adrià
AU  - López Lasanta, María
AU  - Tortosa, Raül
AU  - Julià, Antonio
AU  - Marsal, Sara
PY  - 2015
DO  - 10.1371/journal.pone.0122088
UR  - http://hdl.handle.net/20.500.12105/17088
AB  - OBJECTIVE: Anti-TNF therapies have been highly efficacious in the management of rheumatoid arthritis (RA), but 25-30% of patients do not show a significant clinical response. There is increasing evidence that genetic variation at the Fc receptor...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Antirreumáticos
KW  - Macrófagos
KW  - Polimorfismo de nucleótido único
KW  - Artritis reumatoide
KW  - Receptores de IgG
KW  - Líquido sinovial
KW  - Resultado del tratamiento
KW  - Factor de necrosis tumoral alfa
KW  - Antirheumatic Agents
KW  - Arthritis, Rheumatoid
KW  - Female
KW  - Humans
KW  - Macrophages
KW  - Male
KW  - Polymorphism, Single Nucleotide
KW  - Receptors, IgG
KW  - Synovial Fluid
KW  - Treatment Outcome
KW  - Tumor Necrosis Factor-alpha
KW  - Adult
TI  - Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.
TY  - research article
ER  -