TY  - GEN
AU  - Bueno, Anibal
AU  - Morilla, Ian
AU  - Diez, Diego
AU  - Moya-Garcia, Aurelio A
AU  - Lozano, José
AU  - Ranea, Juan A G
PY  - 2016
DO  - 10.18632/oncotarget.12416
UR  - http://hdl.handle.net/20.500.12105/17115
AB  - RAS proteins are the founding members of the RAS superfamily of GTPases. They are involved in key signaling pathways regulating essential cellular functions such as cell growth and differentiation. As a result, their deregulation by inactivating...
LA  - eng
KW  - Ras
KW  - cancer
KW  - network
KW  - signaling
KW  - therapy
KW  - Molecular interaction database
KW  - Multiple sequence alignment
KW  - K-ras
KW  - Activation
KW  - Inhibitors
KW  - Inhibitors
KW  - Inhibitors
KW  - Discovery
KW  - Target
KW  - Cancer
KW  - Genes
KW  - Bind
KW  - Amino Acid Sequence
KW  - Carrier Proteins
KW  - Computational Biology
KW  - Conserved Sequence
KW  - Databases, Protein
KW  - Humans
KW  - Mutation
KW  - Neoplasms
KW  - Phylogeny
KW  - Protein Binding
KW  - Protein Interaction Mapping
KW  - Protein Interaction Maps
KW  - Signal Transduction
KW  - ras Proteins
TI  - Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies.
TY  - research article
ER  -