TY  - JOUR
AU  - García-Quintáns, Nieves
AU  - Santiago-Sacristan, Silvia
AU  - Márquez-López, Cristina
AU  - Sánchez-Ramos, Cristina
AU  - Martinez-de-Benito, Fernando
AU  - Siniscalco, David
AU  - González-Guerra, Andrés
AU  - Camafeita, Emilio
AU  - Roche-Molina, Marta
AU  - Lytvyn, Mariya
AU  - Morera, David
AU  - Guillen, María I
AU  - Sanguino, María A
AU  - Sanz-Rosa, David
AU  - Martin-Perez, Daniel
AU  - Garcia, Ricardo
AU  - Bernal, Juan Antonio
PY  - 2023
DO  - 10.1038/s41467-023-41981-5
UR  - http://hdl.handle.net/20.500.12105/19255
AB  - The most prevalent genetic form of inherited arrhythmogenic cardiomyopathy (ACM) is caused by mutations in desmosomal plakophilin-2 (PKP2). By studying pathogenic deletion mutations in the desmosomal protein PKP2, here we identify a general mechanism...
LA  - eng
PB  - Nature Publishing Group
KW  - Arrhythmogenic Right Ventricular Dysplasia
KW  - Cardiomyopathies
KW  - Humans
KW  - Actomyosin
KW  - Mutation
KW  - Plakophilins
TI  - MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM).
TY  - journal article
ER  -