TY - GEN AU - Grasselli, J AU - Elez, Elena AU - Caratu, G AU - Matito, J AU - Santos, C AU - Macarulla, T AU - Vidal, J AU - Garcia, M AU - Vieitez, J. M AU - Paez, D AU - Falcó, Esther AU - Lopez Lopez, C AU - Aranda, E AU - Jones, F AU - Sikri, V AU - Nuciforo, P AU - Fasani, Roberta AU - Tabernero, J AU - Montagut, C AU - Azuara, D AU - Dienstmann, R AU - Salazar, R AU - Vivancos, A PY - 2017 DO - 10.1093/annonc/mdx112 SN - 0923-7534 UR - http://hdl.handle.net/20.500.12105/20432 AB - Background: Circulating tumor DNA (ctDNA) is a potential source for tumor genome analysis. We explored the concordance between the mutational status of RAS in tumor tissue and ctDNA in metastatic colorectal cancer (mCRC) patients to establish... LA - eng PB - Oxford University Press KW - anti-EGFR therapy KW - Circulating tumor DNA KW - Metastatic colorectal cancer KW - RAS analysis KW - Mutation KW - Neoplasm Metastasis KW - Colorectal Neoplasms KW - Humans KW - ErbB Receptors KW - Genes, ras TI - Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer TY - research article ER -