TY  - GEN
AU  - García-Rodriguez, Patricia
AU  - Hidalgo, Laura
AU  - Rodriguez-Milla, Miguel A
AU  - Somovilla-Crespo, Beatriz
AU  - Garcia-Castro, Javier
PY  - 2024
DO  - 10.3389/fimmu.2024.1462796
UR  - https://hdl.handle.net/20.500.12105/25566
AB  - LIN28, a highly conserved RNA-binding protein that acts as a posttranscriptional modulator, plays a vital role in the regulation of T-cell development, reprogramming, and immune activity in infectious diseases and T-cell-based immunotherapies. LIN28...
LA  - eng
PB  - Frontiers Media
KW  - CAR T
KW  - LIN28
KW  - Immunotherapy
KW  - Let-7
KW  - Osteosarcoma
KW  - Animals
KW  - Cell Line, Tumor
KW  - Cytotoxicity, Immunologic
KW  - Humans
KW  - Immunotherapy, Adoptive
KW  - Mice
KW  - MicroRNAs
KW  - NK Cell Lectin-Like Receptor Subfamily K
KW  - RNA-Binding Proteins
KW  - Receptors, Chimeric Antigen
KW  - T-Lymphocytes
KW  - Up-Regulation
KW  - Xenograft Model Antitumor Assays
KW  - Neoplasms
TI  - LIN28 upregulation in primary human T cells impaired CAR T antitumoral activity
TY  - research article
ER  -