TY - GEN AU - Silva-Rojas, Roberto AU - Vicente, Natalia AU - Gavilán-Herrera, Manuel AU - Labrador-Cantarero, Verónica AU - Sicilia, Jon AU - Giménez-Sáez, Olga AU - Dumitru, Andra C AU - Sánchez, Mateo I AU - Gato-Vilaseca, Mara AU - Velázquez-Carreras, Diana AU - López, Juan Antonio AU - Vázquez, Jesús AU - Herrero-Galán, Elías AU - López-Unzu, Miguel A AU - Pricolo, Maria Rosaria AU - Alegre-Cebollada, Jorge PY - 2025 UR - https://hdl.handle.net/20.500.12105/27059 AB - Titin, the elastic protein scaffold of muscle sarcomeres, has multifunctional roles in mechanosignalling and is implicated in muscle disease. However, the consequences of disrupting titin's mechanical function in vivo remain incompletely understood.... LA - eng PB - NATURE TI - Mechanically knocking out titin reveals protein tension loss as a trigger of muscle disease. TY - research article ER -