TY  - JOUR
AU  - Tummala, Krishna S
AU  - Gomes, Ana L
AU  - Yilmaz, Mahmut
AU  - Graña, Osvaldo
AU  - Bakiri, Latifa
AU  - Ruppen, Isabel
AU  - Ximénez-Embún, Pilar
AU  - Sheshappanavar, Vinayata
AU  - Rodriguez-Justo, Manuel
AU  - Pisano, David G
AU  - Wagner, Erwin F
AU  - Djouder, Nabil
PY  - 2014
DO  - 10.1016/j.ccell.2014.10.002
UR  - http://hdl.handle.net/20.500.12105/17547
AB  - Molecular mechanisms responsible for hepatocellular carcinoma (HCC) remain largely unknown. Using genetically engineered mouse models, we show that hepatocyte-specific expression of unconventional prefoldin RPB5 interactor (URI) leads to a multistep...
LA  - eng
PB  - Elsevier
KW  - DNA Damage
KW  - Animals
KW  - Carcinoma, Hepatocellular
KW  - Diethylnitrosamine
KW  - Gene Expression Regulation, Neoplastic
KW  - Hepatocytes
KW  - Humans
TI  - Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
TY  - journal article
ER  -