TY - GEN AU - Rochano-Ortiz, Antonio AU - San Sebastián-Jaraba, Irene AU - Zamora, Carmen AU - Simó, Carolina AU - García-Cañas, Virginia AU - Martínez-Albaladejo, Sacramento AU - Fernández-Gómez, María José AU - Marcos-Ríos, Daniel AU - Martínez-Núñez, Patricia AU - Martín-Lorenzo, Marta AU - Velho, Tiago R AU - Ruíz-Rodríguez, María Jesús AU - Leal-Zafra, Amanda AU - Gabandé-Rodríguez, Enrique AU - Martínez-Martínez, Sara AU - Guala, Andrea AU - Lorenzo, Óscar AU - Blanco-Colio, Luis Miguel AU - Martín-Ventura, José Luís AU - Álvarez-Llamas, Gloria AU - Aldamiz-Echevarría, Gonzalo AU - Teixidó-Tura, Gisela AU - Forteza, Alberto AU - Nistal, Juan Francisco AU - Redondo, Juan Miguel AU - Méndez-Barbero, Nerea AU - Mittelbrunn, María AU - Oller, Jorge PY - 2025 UR - https://hdl.handle.net/20.500.12105/27161 AB - Thoracic aortic aneurysms and dissections (TAADs) are depicted by aortic medial degeneration characterized by glycan-rich matrix accumulation. Marfan syndrome (MFS) is the most common inherited connective tissue disorder associated with TAAD. Although... LA - eng PB - Oxford University Press KW - Aortic medial degeneration KW - Hexosamine Biosynthetic pathway KW - Integrated stress response KW - Marfan Syndrome KW - Thoracic aortic aneurysm TI - Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response. TY - research article ER -