TY  - JOUR
AU  - Costa-Machado, Luis Filipe
AU  - Martín-Hernández, Roberto
AU  - Sanchez-Luengo, Miguel Ángel
AU  - Hess, Katharina
AU  - Vales-Villamarin, Claudia
AU  - Barradas, Marta
AU  - Lynch, Cian
AU  - de la Nava, Daniel
AU  - Diaz-Ruiz, Alberto
AU  - de Cabo, Rafael
AU  - Cañamero, Marta
AU  - Martinez Garcia, Maria Dolores
AU  - Sanchez-Carbayo, Marta
AU  - Herranz, Daniel
AU  - Serrano, Manuel
AU  - Fernandez-Marcos, Pablo J
PY  - 2018
DO  - 10.15252/embr.201643879
UR  - http://hdl.handle.net/20.500.12105/17422
AB  - The NAD+-dependent deacetylase SIRT1 can be oncogenic or tumor suppressive depending on the tissue. Little is known about the role of SIRT1 in non-small cell lung carcinoma (NSCLC), one of the deadliest cancers, that is frequently associated with...
LA  - eng
PB  - EMBO Press
KW  - Adenocarcinoma of Lung
KW  - Alveolar Epithelial Cells
KW  - Animals
KW  - Carcinogenesis
KW  - Carcinoma, Non-Small-Cell Lung
KW  - Cell Line, Tumor
KW  - Cells, Cultured
KW  - Down-Regulation
KW  - Fibroblasts
KW  - Humans
KW  - Lung Neoplasms
KW  - Mice
KW  - Mitogen-Activated Protein Kinases
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - Phosphatidylinositol 3-Kinases
KW  - Progression-Free Survival
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Sirtuin 1
TI  - Sirt1 protects from K-Ras-driven lung carcinogenesis.
TY  - journal article
ER  -