TY - GEN AU - Segovia-Zafra, Antonio AU - Di Zeo-Sánchez, Daniel E. AU - López-Gómez, Carlos AU - Pérez-Valdés, Zeus AU - García-Fuentes, Eduardo AU - Andrade, Raúl J. AU - Lucena, M. Isabel AU - Villanueva-Paz, Marina PY - 2021 DO - 10.1016/j.apsb.2021.11.013 UR - http://hdl.handle.net/20.500.12105/18225 AB - Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of drug... LA - eng PB - Elsevier KW - Drug-induced liver injury KW - Preclinical models KW - Mechanisms KW - Oxidative stress KW - Mitochondrial damage KW - Immune response KW - Personalized medicine KW - Enfermedad hepática inducida por sustancias y drogas KW - Estrés oxidativo KW - Inmunidad KW - Medicina de precisión KW - Humans KW - Animals KW - Public Health KW - Nonprescription Drugs KW - Dietary Supplements KW - Models, Theoretical KW - Prescriptions KW - Biomarkers, Pharmacological KW - Prognosis TI - Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction TY - review article ER -