TY  - GEN
AU  - Ramos-Sevillano, Elisa
AU  - Urzainqui, Ana
AU  - Campuzano, Susana
AU  - Moscoso, Miriam
AU  - Gonzalez-Camacho, Fernando
AU  - Domenech Lucas, Mirian
AU  - Rodriguez de Cordoba, Santiago
AU  - Sánchez Madrid, Francisco
AU  - Brown, Jeremy S
AU  - García, Ernesto
AU  - Yuste, Jose Enrique
PY  - 2015
DO  - 10.1128/IAI.02811-14
SN  - 0019-9567
UR  - http://hdl.handle.net/20.500.12105/8592
AB  - The complement system is a key component of the host immune response for the recognition and clearance of Streptococcus pneumoniae. In this study, we demonstrate that the amidase LytA, the main pneumococcal autolysin, inhibits complement-mediated...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Animals
KW  - Bacterial Capsules
KW  - Bacterial Proteins
KW  - Cell Wall
KW  - Complement Activation
KW  - Complement C3
KW  - Complement Factor H
KW  - Histocompatibility Antigens
KW  - Host-Pathogen Interactions
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - N-Acetylmuramoyl-L-alanine Amidase
KW  - Phagocytosis
KW  - Phosphorylcholine
KW  - Pneumococcal Infections
KW  - Polysaccharides, Bacterial
KW  - Sepsis
KW  - Streptococcus pneumoniae
KW  - Streptolysins
TI  - Pleiotropic effects of cell wall amidase LytA on Streptococcus pneumoniae sensitivity to the host immune response
TY  - research article
ER  -