TY - JOUR AU - Corella, Dolores AU - Sorli, Jose V. AU - Gonzlez, Jose I. AU - Ortega, Carolina AU - Fit, Montserrat AU - Bull, Monica AU - Martinez-Gonzalez, Miguel Angel AU - Ros, Emilio AU - Ars, Fernando AU - Lapetra, Jose AU - Gmez-Gracia, Enrique AU - Serra-Majem, Lluis AU - Ruiz-Gutierrez, Valentina AU - Fiol, Miquel AU - Coltell, Oscar AU - Vinyoles, Ernest AU - Pinto, Xavier AU - Marti, Amelia AU - Saiz, Carmen AU - Ordovas, Jose M AU - Estruch, Ramn PY - 2014 DO - 10.1186/1475-2840-13-5 SN - 1475-2840 UR - http://hdl.handle.net/20.500.12105/6518 AB - Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related to obesity, its association... LA - eng PB - BioMed Central (BMC) KW - Heart rate KW - FAIM2 KW - Apoptosis KW - BODY-MASS INDEX KW - GENOME-WIDE ASSOCIATION KW - CORONARY-ARTERY-DISEASE KW - CARDIOVASCULAR-DISEASE KW - JAPANESE POPULATION KW - MEDITERRANEAN DIET KW - CAUSE MORTALITY KW - SOLUBLE FAS KW - VARIANTS KW - LOCI KW - Diabetes Mellitus, Type 2 KW - Genetic Predisposition to Disease KW - Aged KW - Alleles KW - Follow-Up Studies KW - Heart Rate KW - Humans KW - Middle Aged KW - Obesity KW - Longitudinal Studies KW - Membrane Proteins KW - Myocardial Infarction KW - Male KW - Female KW - Risk Factors KW - Risk Factors KW - Diet, Mediterranean KW - Genetic Association Studies KW - Apoptosis Regulatory Proteins KW - Polymorphism, Genetic TI - Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial TY - journal article ER -