TY - GEN AU - Lima-Cabello, Elena AU - Garcia-Guirado, Francisco AU - Calvo-Medina, Rocio AU - el Bekay, Rajaa AU - Perez-Costillas, Lucia AU - Quintero-Navarro, Carolina AU - Sanchez-Salido, Lourdes AU - de Diego-Otero, Yolanda PY - 2016 DO - 10.1155/2016/8548910 UR - http://hdl.handle.net/20.500.12105/17117 AB - BACKGROUND: Fragile X syndrome is the most common genetic cause of mental disability. Although many research has been performed, the mechanism underlying the pathogenesis is unclear and needs further investigation. Oxidative stress played major roles... LA - eng PB - Hindawi KW - Animales KW - Encéfalo KW - Modelos de enfermedad en animales KW - Síndrome del cromosoma X frágil KW - Masculino KW - Ratones KW - Ratones noqueados KW - Óxido nítrico KW - Óxido nítrico sintasa KW - Estrés oxidativo KW - Isoformas de proteínas KW - ARN mensajero KW - Factor de transcripción ReIA KW - Tirosina KW - Animals KW - Brain KW - Disease Models, Animal KW - Fragile X Syndrome KW - Male KW - Mice KW - Mice, Knockout KW - NF-kappa B KW - Nitric Oxide KW - Nitric Oxide Synthase KW - Oxidative Stress KW - RNA, Messenger KW - Transcription Factor RelA KW - Tyrosine TI - An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability. TY - research article ER -