TY - JOUR AU - Tinaquero, David AU - Crespo-García, Teresa AU - Utrilla, Raquel G AU - Nieto-Marín, Paloma AU - González-Guerra, Andrés AU - Rubio-Alarcón, Marcos AU - Cámara-Checa, Anabel AU - Dago, María AU - Matamoros, Marcos AU - Pérez-Hernández, Marta AU - Tamargo, María AU - Cebrián, Jorge AU - Jalife, Jose AU - Tamargo, Juan AU - Bernal, Juan Antonio AU - Caballero, Ricardo AU - Delpón, Eva PY - 2020 DO - 10.1038/s41598-020-67109-z UR - http://hdl.handle.net/20.500.12105/11056 AB - Synapse-Associated Protein 97 (SAP97) is an anchoring protein that in cardiomyocytes targets to the membrane and regulates Na+ and K+ channels. Here we compared the electrophysiological effects of native (WT) and p.P888L SAP97, a common polymorphism.... LA - eng PB - Nature Publishing Group TI - The p.P888L SAP97 polymorphism increases the transient outward current (Ito,f) and abbreviates the action potential duration and the QT interval. TY - journal article ER -