TY - GEN AU - Sánchez-Menéndez, Clara AU - Rodríguez-Pérez, Jaime AU - Fuertes, Daniel AU - Leguizamon, Valentina AU - González-Sanmartín, María AU - Mateos, Elena AU - Cervero, Miguel AU - San José, Esther AU - Sanz, Gonzalo AU - Álvaro, Edurne AU - Ballestero-Pérez, Araceli AU - Martí-Gallostra, Marc AU - Rueda, José Antonio AU - Hurtado-Caballero, Elena AU - Pastor, Carlos AU - Balaguer, Francesc AU - Spinelli, Antonino AU - Martinez-Laso, Jorge AU - Torres, Montserrat AU - Perea, José AU - Coiras, Mayte AU - Spanish EOCRC Consortium (SECOC) PY - 2025 DO - 10.3389/fimmu.2025.1692382 SN - 1664-3224 UR - https://hdl.handle.net/20.500.12105/27056 AB - Introduction: Colorectal cancer (CRC) is a leading cause of cancer-related mortality. While screening has reduced incidence in older adults, cases of early-onset CRC (EOCRC), diagnosed before age 50, are rising, highlighting the need to understand its... LA - eng PB - Frontiers Media KW - Colorectal neoplasms KW - Early diagnosis KW - Immune response KW - T-cell subsets KW - Cytokine profiling KW - Immune biomarkers TI - Differences in the peripheral blood immune landscape between early-onset and late-onset colorectal cancer TY - research article ER -