TY  - GEN
AU  - Arora, Mansi
AU  - Moser, Justin
AU  - Hoffman, Timothy E
AU  - Watts, Lotte P
AU  - Min, Mingwei
AU  - Musteanu, Mónica
AU  - Rong, Yao
AU  - Ill, C Ryland
AU  - Nangia, Varuna
AU  - Schneider, Jordan
AU  - Sanclemente, Manuel
AU  - Lapek, John
AU  - Nguyen, Lisa
AU  - Niessen, Sherry
AU  - Dann, Stephen
AU  - VanArsdale, Todd
AU  - Barbacid, Mariano
AU  - Miller, Nichol
AU  - Spencer, Sabrina L
PY  - 2023
UR  - https://hdl.handle.net/20.500.12105/26787
AB  - CDK2 is a core cell-cycle kinase that phosphorylates many substrates to drive progression through the cell cycle. CDK2 is hyperactivated in multiple cancers and is therefore an attractive therapeutic target. Here, we use several CDK2 inhibitors in...
LA  - eng
PB  - Cell Press
KW  - CDK plasticity
KW  - CDK2
KW  - CDK4/6
KW  - PF-06873600
KW  - PF-07104091
KW  - Palbociclib
KW  - Rb
KW  - cyclin A
KW  - drug adaptation
KW  - restriction point
TI  - Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.
TY  - research article
ER  -