TY - GEN AU - Fraga, Mario F AU - Ballestar, Esteban AU - Villar-Garea, Ana AU - Boix-Chornet, Manuel AU - Espada, Jesus AU - Schotta, Gunnar AU - Bonaldi, Tiziana AU - Haydon, Claire AU - Ropero, Santiago AU - Petrie, Kevin AU - Iyer, N Gopalakrishna AU - Pérez-Rosado, Alberto AU - Calvo, Enrique AU - Lopez, Juan A AU - Cano, Amparo AU - Calasanz, Maria J AU - Colomer, Dolors AU - Piris, Miguel Angel AU - Ahn, Natalie AU - Imhof, Axel AU - Caldas, Carlos AU - Jenuwein, Thomas AU - Esteller, Manel PY - 2005 UR - https://hdl.handle.net/20.500.12105/27221 AB - CpG island hypermethylation and global genomic hypomethylation are common epigenetic features of cancer cells. Less attention has been focused on histone modifications in cancer cells. We characterized post-translational modifications to histone H4 in... LA - eng PB - Nature Publishing Group TI - Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. TY - research article ER -