TY  - JOUR
AU  - Lopez, Daniel
AU  - Gil-Torregrosa, Beatriz C.
AU  - Bergmann, Cornelia
AU  - Val, Margarita del
PY  - 2000
DO  - 10.4049/jimmunol.164.10.5070
SN  - 0022-1767
UR  - http://hdl.handle.net/20.500.12105/10781
AB  - Antigenic peptides derived from viral proteins by multiple proteolytic cleavages are bound by MHC class I molecules and recognized by CTL. Processing predominantly takes place in the cytosol of infected cells by the action of proteasomes. To identify...
LA  - eng
KW  - Antigen Presentation
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - Acetylcysteine
KW  - Animals
KW  - Cell Line, Transformed
KW  - Cysteine Endopeptidases
KW  - Cysteine Proteinase Inhibitors
KW  - Epitopes, T-Lymphocyte
KW  - HIV Envelope Protein gp160
KW  - HIV-1
KW  - Hepatitis B e Antigens
KW  - Histocompatibility Antigens Class I
KW  - Humans
KW  - Hydrolysis
KW  - Leupeptins
KW  - Metalloendopeptidases
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Multienzyme Complexes
KW  - Pepstatins
KW  - Peptide Fragments
KW  - Proteasome Endopeptidase Complex
KW  - Protein Processing, Post-Translational
KW  - Recombinant Fusion Proteins
KW  - Signal Transduction
KW  - T-Lymphocytes, Cytotoxic
TI  - Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.
TY  - journal article
ER  -