TY - JOUR AU - Denise, Hubert AU - Poot, Jacqueline AU - Jimenez, Maribel AU - Ambit, Audrey AU - Herrmann, Daland C AU - Vermeulen, Arno N AU - Coombs, Graham H AU - Mottram, Jeremy C PY - 2006 DO - 10.1186/1471-2199-7-42 SN - 14712199 UR - http://hdl.handle.net/20.500.12105/7028 AB - BACKGROUND: Visceral leishmaniasis caused by members of the Leishmania donovani complex is often fatal in the absence of treatment. Research has been hampered by the lack of good laboratory models and tools for genetic manipulation. In this study, we... LA - eng PB - BioMed Central (BMC) KW - Amino Acid Sequence KW - Animals KW - Blotting, Southern KW - Cricetinae KW - Cysteine Endopeptidases KW - Dogs KW - Gene Deletion KW - Gene Expression Regulation, Enzymologic KW - Genome, Protozoan KW - Humans KW - Leishmania infantum KW - Leishmania mexicana KW - Leishmaniasis, Visceral KW - Mesocricetus KW - Molecular Sequence Data KW - Mutation KW - Protozoan Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sequence Homology, Amino Acid KW - U937 Cells TI - Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5 TY - journal article ER -