TY - JOUR AU - Ramos-Sevillano, Elisa AU - Rodriguez-Sosa, Cinthya AU - Cafini, Fabio AU - Giménez, Maria-Jose AU - Navarro, Ana AU - Sevillano, David AU - Alou, Luis AU - García, Ernesto AU - Aguilar, Lorenzo AU - Yuste, Jose Enrique PY - 2012 DO - 10.1371/journal.pone.0044135 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/6831 AB - BACKGROUND: Specific antibodies mediate humoral and cellular protection against invading pathogens such as Streptococcus pneumoniae by activating complement mediated immunity, promoting phagocytosis and stimulating bacterial clearance. The emergence... LA - eng PB - Public Library of Science (PLOS) KW - Acute-Phase Proteins KW - Animals KW - Anti-Bacterial Agents KW - Antibodies KW - Ceftriaxone KW - Cephalosporins KW - Complement Activation KW - Complement C1q KW - Complement C3c KW - Drug Resistance, Microbial KW - Egtazic Acid KW - Flow Cytometry KW - Humans KW - Immune System KW - Mice KW - Phagocytosis KW - Streptococcus pneumoniae KW - beta-Lactams TI - Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains TY - journal article ER -