TY - GEN AU - Capdevila, J AU - Hernando, J AU - Teule, A AU - Lopez, C AU - Garcia-Carbonero, R AU - Benavent, M AU - Custodio, A AU - Garcia-Alvarez, A AU - Cubillo, A AU - Alonso, V AU - Carmona-Bayonas, A AU - Alonso-Gordoa, T AU - Crespo, G AU - Jimenez-Fonseca, P AU - Blanco, M AU - Viudez, A AU - La Casta, A AU - Sevilla, I AU - Segura, A AU - Llanos, M AU - Landolfi, S AU - Nuciforo, P AU - Manzano, J L AU - GarcĂ­a-Carbonero, Rocio PY - 2023 DO - 10.1038/s41467-023-38611-5 UR - https://hdl.handle.net/20.500.12105/23118 AB - Single immune checkpoint blockade in advanced neuroendocrine neoplasms (NENs) shows limited efficacy; dual checkpoint blockade may improve treatment activity. Dune (NCT03095274) is a non-randomized controlled multicohort phase II clinical trial... LA - eng PB - Nature Publishing Group KW - Neuroendocrine Tumors KW - Carcinoid Tumor KW - Humans KW - B7-H1 Antigen KW - Lung TI - Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin TY - research article ER -