TY  - GEN
AU  - González-Cofrade, Laura
AU  - Green, Jack P
AU  - Cuadrado, Irene
AU  - Amesty, Ángel
AU  - Oramas-Royo, Sandra
AU  - Brough, David
AU  - Estévez-Braun, Ana
AU  - Hortelano, Sonsoles
AU  - de Las Heras, Beatriz
PY  - 2023
DO  - 10.1016/j.bioorg.2023.106362
UR  - http://hdl.handle.net/20.500.12105/17376
AB  - Dysregulated inflammasome activity, particularly of the NLRP3 inflammasome, is associated with the development of several inflammatory diseases. The study of molecules directly targeting NLRP3 is an emerging field in the discovery of new therapeutic...
LA  - eng
PB  - Elsevier
KW  - Nor-friedelane triterpenes
KW  - Maytenus retusa
KW  - NLRP3 inflammasome
KW  - ASC
KW  - Pyroptosis
KW  - IL-1β
KW  - Macrophages
KW  - Inflammasomes
KW  - Triterpenes
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Phenols
KW  - Anti-Inflammatory Agents
TI  - Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors
TY  - research article
ER  -