TY - JOUR AU - Olbrich, Teresa AU - Mayor-Ruiz, Cristina AU - Vega-Sendino, Maria AU - Gomez, Carmen AU - Ortega, Sagrario AU - Ruiz, Sergio AU - Fernandez-Capetillo, Oscar PY - 2017 DO - 10.1073/pnas.1705133114 UR - http://hdl.handle.net/20.500.12105/17680 AB - The recent development of haploid cell lines has facilitated forward genetic screenings in mammalian cells. These lines include near-haploid human cell lines isolated from a patient with chronic myelogenous leukemia (KBM7 and HAP1), as well as haploid... LA - eng PB - National Academy of Sciences KW - Haploidy KW - Animals KW - Cell Line KW - Cell Proliferation KW - Cell Survival KW - Chromosome Segregation KW - Humans KW - Mice KW - Mouse Embryonic Stem Cells KW - Tumor Suppressor Protein p53 TI - A p53-dependent response limits the viability of mammalian haploid cells. TY - journal article ER -