TY - JOUR AU - Gonzalez Portal, Maria Eugenia PY - 2017 DO - 10.3390/ijms18010126 SN - 1422-0067 UR - http://hdl.handle.net/20.500.12105/5767 AB - The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for antiretroviral drug development. The conservation both of the structure along virus evolution and the amino acid sequence in viral isolates from patients... LA - eng PB - Molecular Diversity Preservation International KW - Vpr protein KW - Antiretroviral target KW - Cellular metabolism KW - Mechanism of action KW - Pathogenesis KW - Animals KW - Anti-HIV Agents KW - Carrier Proteins KW - Conserved Sequence KW - Disease Progression KW - Drug Discovery KW - Evolution, Molecular KW - HIV Infections KW - HIV-1 KW - Humans KW - Lentiviruses, Primate KW - Protein Binding KW - Virus Replication KW - vpr Gene Products, Human Immunodeficiency Virus TI - The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention TY - journal article ER -