TY  - JOUR
AU  - Olmedo, Dionisio A
AU  - López-Pérez, José Luis
AU  - Del Olmo, Esther
AU  - Bedoya, Luis M
AU  - Sancho, Rocío
AU  - Alcamí, José
AU  - Muñoz, Eduardo
AU  - Feliciano, Arturo San
AU  - Gupta, Mahabir P
PY  - 2017
DO  - 10.3390/molecules22020321
SN  - 1420-3049
UR  - http://hdl.handle.net/20.500.12105/7183
AB  - Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase reporter gene. Inhibition of HIV transcription and Tat function were...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - 4-phenyl-chromen-one
KW  - AIDS
KW  - NF-κB inhibition
KW  - Tat protein
KW  - Anti-HIV activity
KW  - Neoflavonoids
KW  - Anti-HIV Agents
KW  - Biflavonoids
KW  - HIV Infections
KW  - HIV-1
KW  - Humans
KW  - Microbial Sensitivity Tests
KW  - Molecular Structure
KW  - NF-kappa B
KW  - Signal Transduction
KW  - Virus Replication
KW  - tat Gene Products, Human Immunodeficiency Virus
TI  - Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways
TY  - journal article
ER  -