TY - GEN AU - Jimenez-Sousa, Maria Angeles AU - Medrano, Luz Maria AU - Liu, Pilar AU - Almansa, Raquel AU - Fernandez-Rodriguez, Amanda AU - Gómez-Sánchez, Esther AU - Rico, Lucía AU - Heredia-Rodríguez, María AU - Gómez-Pesquera, Estefanía AU - Tamayo, Eduardo AU - Resino, Salvador PY - 2017 DO - 10.1111/eci.12702 UR - http://hdl.handle.net/20.500.12105/17240 AB - Background: IL-1β is a primary mediator of systemic inflammatory response syndrome (SIRS) and it may lead to shock septic. Our aim was to analyse whether IL-1B rs16944 polymorphism is associated with the onset of septic shock and death after major... LA - eng PB - Wiley KW - Death KW - IL-1B KW - Major surgery KW - Septic shock KW - SNPs KW - Systemic inflammatory response syndrome KW - Cardiac Surgical Procedures KW - Aged KW - Case-Control Studies KW - Female KW - Gene Frequency KW - Genotype KW - Humans KW - Interleukin-1beta KW - Logistic Models KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Odds Ratio KW - Polymorphism, Single Nucleotide KW - Postoperative Complications KW - Shock, Septic KW - Surgical Procedures, Operative TI - IL-1B rs16944 polymorphism is related to septic shock and death TY - research article ER -