TY  - GEN
AU  - López-Cortés, Luis Eduardo
AU  - Rosso-Fernández, Clara
AU  - Núñez-Núñez, María
AU  - Lavín-Alconero, Lucía
AU  - Bravo-Ferrer, José
AU  - Barriga, Ángel
AU  - Delgado, Mercedes
AU  - Lupión, Carmen
AU  - Retamar, Pilar
AU  - Rodríguez-Baño, Jesús
AU  - SIMPLIFY Study Group
PY  - 2017
DO  - 10.1136/bmjopen-2016-015439
UR  - https://hdl.handle.net/20.500.12105/25224
AB  - Introduction: Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one of the proposed strategies for reducing the unnecessary use of broad-spectrum antibiotics (BSA). The empirical treatment of...
LA  - eng
KW  - Enterobacteriaceae
KW  - De-escalation
KW  - Antimicrobial stewardship
KW  - Bloodstream infection
KW  - Broad-spectrum antibiotics
KW  - Anti-Bacterial Agents
KW  - Bacteremia
KW  - Drug Administration Routes
KW  - Enterobacteriaceae
KW  - Enterobacteriaceae Infections
KW  - Humans
KW  - Microbial Sensitivity Tests
KW  - Pseudomonas
KW  - Pseudomonas Infections
KW  - Research Design
KW  - Treatment Outcome
KW  - beta-Lactams
TI  - Targeted simplification versus antipseudomonal broad-spectrum beta-lactams in patients with bloodstream infections due to Enterobacteriaceae (SIMPLIFY): a study protocol for a multicentre, open-label, phase III randomised, controlled, non-inferiority clinical trial.
TY  - research article
ER  -