TY - JOUR AU - Pascual, Tomas AU - Apellániz-Ruiz, María AU - Pernaut, Cristina AU - Cueto-Felgueroso, Cecilia AU - Villalba, Pablo AU - Álvarez, Carlos AU - Manso, Luis AU - Inglada Perez, Lucia AU - Robledo Batanero, Mercedes AU - Rodriguez Antona, Cristina AU - Ciruelos, Eva PY - 2017 DO - 10.1371/journal.pone.0180192 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/5275 AB - PURPOSE: Metastatic breast cancer (MBC) progressing after endocrine therapy frequently activates PI3K/AKT/mTOR pathway. The BOLERO-2 trial showed that everolimus-exemestane achieves increased progression free survival (PFS) compared with exemestane.... LA - eng KW - Adult KW - Aged KW - Antineoplastic Agents KW - Breast Neoplasms KW - Disease-Free Survival KW - Everolimus KW - Female KW - Genotype KW - Humans KW - Middle Aged KW - Pharmacogenetics KW - Prognosis KW - Survival Rate KW - Treatment Outcome KW - Polymorphism, Single Nucleotide TI - Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer TY - journal article ER -