TY - GEN AU - Badenes, Rafael AU - Hutton, Brian AU - Citerio, Giuseppe AU - Robba, Chiara AU - Aguilar, Gerardo AU - Alonso-Arroyo, Adolfo AU - Taccone, Fabio Silvio AU - Tornero, Carlos AU - Catalá-López, Ferrán PY - 2020 DO - 10.1136/bmjopen-2019-033913 SN - 2044-6055 UR - http://hdl.handle.net/20.500.12105/9111 AB - INTRODUCTION: Acute brain injury is a challenging public health problem worldwide. Elevated intracranial pressure is a common complication after acute brain injury. Hyperosmolar therapy is one of the main therapeutic strategies for the management of... LA - eng PB - BMJ Publishing Group KW - Brain injury KW - Hyperosmolar therapy KW - Hypertonic saline KW - Mannitol KW - Meta-analysis KW - Systematic review TI - Hyperosmolar therapy for acute brain injury: study protocol for an umbrella review of meta-analyses and an evidence mapping TY - review article ER -