TY - JOUR AU - Gupta, Jalaj AU - Igea, Ana AU - Papaioannou, Marilena AU - Lopez-Casas, Pedro Pablo AU - Llonch, Elisabet AU - Hidalgo, Manuel AU - Gorgoulis, Vassilis G AU - Nebreda, Angel R PY - 2015 DO - 10.18632/oncotarget.3816 UR - http://hdl.handle.net/20.500.12105/10691 AB - Colorectal cancer is a major health problem and the second cause of cancer related death in western countries. Signaling pathways that control tissue homeostasis are often deregulated during tumorigenesis and contribute to tumor development. Studies... LA - eng PB - Impact Journals KW - COLORECTAL-CANCER GROWTH KW - CELL-PROLIFERATION KW - IN-VIVO KW - INFLAMMATION-DRIVEN KW - STAT3 ACTIVATION KW - PROTEIN-KINASE KW - P38-ALPHA KW - SURVIVAL KW - MODELS KW - EXPRESSION KW - Adenocarcinoma KW - Animals KW - Antineoplastic Agents KW - Benzamides KW - Carcinoma, Neuroendocrine KW - Cell Differentiation KW - Colonic Neoplasms KW - Cytokines KW - Genes, ras KW - Humans KW - Liver Neoplasms KW - MAP Kinase Signaling System KW - Mice KW - Mice, Nude KW - Mutation KW - Neoplasm Proteins KW - Neoplasm Staging KW - Protein Kinase Inhibitors KW - Pyridones KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays KW - p38 Mitogen-Activated Protein Kinases TI - Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. TY - journal article ER -