TY  - JOUR
AU  - Díaz-Talavera, Alberto
AU  - Calvo, Patricia A
AU  - Gonzalez-Acosta, Daniel
AU  - Díaz, Marcos
AU  - Sastre-Moreno, Guillermo
AU  - Blanco-Franco, Luis
AU  - Guerra, Susana
AU  - Martínez-Jiménez, Maria I
AU  - Mendez, Juan
AU  - Blanco, Luis
PY  - 2019
DO  - 10.1038/s41598-018-37439-0
SN  - 2045-2322
UR  - http://hdl.handle.net/20.500.12105/7673
AB  - PrimPol is a human primase/polymerase specialized in re-starting stalled forks by repriming beyond lesions such as pyrimidine dimers, and replication-perturbing structures including G-quadruplexes and R-loops. Unlike most conventional primases,...
LA  - eng
PB  - Nature Publishing Group
KW  - DNA-POLYMERASE
KW  - ENZYME
KW  - RIBONUCLEOTIDE INCORPORATION
KW  - KINETIC-ANALYSIS
KW  - REPLICATION
KW  - PRIMASE
KW  - GENOME
KW  - RNA
KW  - NUCLEOTIDE
KW  - PROTEIN
TI  - A cancer-associated point mutation disables the steric gate of human PrimPol
TY  - journal article
ER  -