TY - JOUR AU - Rodriguez-Cortez, Virginia C. AU - Martinez-Redondo, Paloma AU - Catala-Moll, Francesc AU - Rodriguez-Ubreva, Javier AU - Garcia-Gomez, Antonio AU - Poorani-Subramani, Ganesh AU - Ciudad, Laura AU - Hernando, Henar AU - Perez-Garcia, Arantxa AU - Company, Carlos AU - Urquiza, Jose M. AU - Ramiro, Almudena R AU - Di Noia, Javier M. AU - Vaquero, Alejandro AU - Ballestar, Esteban PY - 2017 DO - 10.1038/s41598-017-07380-9 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/5101 AB - Activation-induced cytidine deaminase (AID) triggers antibody diversification in B cells by catalysing deamination and subsequently mutating immunoglobulin (Ig) genes. Association of AID with RNA Pol II and occurrence of epigenetic changes during Ig... LA - eng PB - Nature Publishing Group KW - DOUBLE-STRAND BREAKS KW - SOMATIC HYPERMUTATION KW - SUPER-ENHANCERS KW - RECRUIT AID KW - B-CELLS KW - DNA KW - METHYLATION KW - REGIONS KW - DEMETHYLATION KW - REPAIR TI - Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites TY - journal article ER -