TY - GEN AU - Llinàs-Arias, Pere AU - Ensenyat-Mendez, Miquel AU - Íñiguez-Muñoz, Sandra AU - Orozco, Javier IJ AU - Valdez, Betsy AU - Salomon, Matthew P AU - Matsuba, Chikako AU - Solivellas-Pieras, Maria AU - Bedoya-López, Andrés F AU - Sesé, Borja AU - Mezger, Anja AU - Ormestad, Mattias AU - Unzueta, Fernando AU - Strand, Siri H AU - Boiko, Alexander D AU - Hwang, E Shelley AU - Cortés, Javier AU - DiNome, Maggie L AU - Esteller, Manel AU - Lupien, Mathieu AU - Marzese, Diego M PY - 2023 DO - 10.1186/s12943-023-01906-8 UR - https://hdl.handle.net/20.500.12105/23611 AB - Background: Triple-negative breast cancer (TNBC) is an aggressive subtype that exhibits a high incidence of distant metastases and lacks targeted therapeutic options. Here we explored how the epigenome contributes to matrix metalloprotease (MMP)... LA - eng PB - BioMed Central (BMC) KW - Breast Neoplasms KW - Triple Negative Breast Neoplasms KW - Neoplasm Recurrence, Local KW - Chromatin KW - Female KW - Humans KW - Multigene Family KW - Carcinoma, Intraductal, Noninfiltrating KW - Matrix Metalloproteinase 8 TI - Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors TY - research article ER -