TY  - JOUR
AU  - Trakala, Marianna
AU  - Rodríguez-Acebes, Sara
AU  - Maroto, María
AU  - Symonds, Catherine E
AU  - Santamaria, David
AU  - Malumbres, Marcos
AU  - Ortega Jimenez, Sagrario
AU  - Barbacid, Mariano
AU  - Mendez, Juan
AU  - Malumbres Martinez, Marcos
PY  - 2015
DO  - 10.1016/j.devcel.2014.12.015
UR  - http://hdl.handle.net/20.500.12105/10673
AB  - Polyploidization is a natural process that frequently accompanies differentiation; its deregulation is linked to genomic instability and cancer. Despite its relevance, why cells select different polyploidization mechanisms is unknown. Here we report a...
LA  - eng
PB  - Cell Press
KW  - CYCLIN-DEPENDENT KINASES
KW  - ENDOMITOTIC CELL-CYCLE
KW  - S-PHASE
KW  - RE-REPLICATION
KW  - AURORA B
KW  - GENE AMPLIFICATION;
KW  - GENOMIC STABILITY
KW  - MITOTIC EXIT;
KW  - IN-VIVO;
KW  - CDK1
KW  - Polyploidy
KW  - Anaphase
KW  - Animals
KW  - Cdc20 Proteins
KW  - Cells, Cultured
KW  - Megakaryocytes
KW  - Mice
KW  - Mitosis
KW  - Protein-Serine-Threonine Kinases
TI  - Functional reprogramming of polyploidization in megakaryocytes.
TY  - journal article
ER  -