TY - GEN AU - Granados-Durán, Pablo AU - López-Ávalos, María Dolores AU - Cifuentes, Manuel AU - Pérez-Martín, Margarita AU - Fernández-Arjona, María Del Mar AU - Hughes, Timothy R AU - Johnson, Krista AU - Morgan, B Paul AU - Fernández-Llebrez, Pedro AU - Grondona, Jesús M PY - 2017 DO - 10.3389/fneur.2017.00078 SN - 1664-2295 UR - http://hdl.handle.net/20.500.12105/17293 AB - Some central nervous system pathogens express neuraminidase (NA) on their surfaces. In the rat brain, a single intracerebroventricular (ICV) injection of NA induces myelin vacuolation in axonal tracts. Here, we explore the nature, the time course, and... LA - eng KW - C5a KW - C6-deficient rats KW - anti-C5 KW - brain KW - complement system KW - myelin vacuolation KW - neuraminidase KW - neuroinflammation TI - Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation. TY - research article ER -